| | | الدكتور قيس الاوقاتي استاذ امراض الكلى العراقي |  |
| | | كاتب الموضوع | رسالة |
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Dr.Hannani Maya
المشرف العام
الدولة : 
الجنس : 
عدد المساهمات : 60577
مزاجي : 
تاريخ التسجيل : 21/09/2009
الابراج : 
 العمل/الترفيه : الأنترنيت والرياضة والكتابة والمطالعة
 | موضوع: الدكتور قيس الاوقاتي استاذ امراض الكلى العراقي  الثلاثاء 23 يونيو 2015 - 0:42 | |
| الدكتور قيس الاوقاتي استاذ امراض الكلى العراقي [size=32]الدكتور قيس الاوقاتي من مواليد1938 العراق تخرج من كلية طب بغداد عام1962[/size]  حاصل على العديد من الزمالات الطبية الامريكية في مجال امراض الكلى استاذ لمادة امراض الكلى في العديد من المدارس والكلية الطبية الامريكية له العشرات من المؤلفات الطبية والكتب الطبية في علاج امراض الكلىباحث نشط له العديد من البحوث المتطورة في مجال الكلى وامراض الكلي تدرب بين يديه المئات من طلاب الطب والعشرات من اختصاصي امراض الكلى في امريكا حاصل على عدد من الجوائز العالمية والمحليةشارك في العديد من المؤتمرات الطبية عالم واستاذ ناجح في امراض الكلىمفخرة من مفاخر علماء العراق ومن الاطباء المتميزين في علاج امراض الكلى  [size=32] Qais Al-Awqati[/size] , M.B., Ch.B.Prof. of NephrologyResearch SummaryEpithelial Cell Biology, Kidney Development, Stem Cells.Research ActivitiesEpithelial Differentiation During development epithelia cells are generated from non-epithelial stem cells. These epithelia all have tight junction and apical and basal polarity. Mature epithelia however are easy to recognize as being tissue-specific. This implies that a second differentiation signal is needed to specify these terminally differentiated phenotypes. We have discovered a pathway for terminal differentiation of epithelia cells. Starting with a kidney cell line, we found that an extracellular matrix protein, which we termed hensin induces terminal differentiation in epithelial cells. This protein is expressed in most epithelia. Hensin requires to be localized in the matrix to bind to tis receptor. Knockout of hensin caused defects in the terminal differentiation of the earliest embryonic epithelia.Kidney Development During nephrogenesis, a set of mesenchyma cells convert to epithelia and then segment to form the nephron. We are studying the processes that generate and determine the segment identity and the number of nephrons.Stem Cells We have recently identified that the mature kidney contains stem cells. We are presently isolating these stem cells with a view towards characterizing their transcriptional program.Positions & Appointments1987-present Robert F. Loeb Professor of Medicine Columbia University, College of Physicians & Surgeons New York, NY1983-present Professor of Physiology Columbia University, College of Physicians & Surgeons New York, NY1983-present Professor of Medicine Columbia University, College of Physicians & Surgeons New York, NY1981-83 Associate Professor of Medicine Columbia University, College of Physicians & Surgeons New York, NY1977-81 Associate Professor of Physiology Columbia University, College of Physicians & Surgeons New York, NYEducation and Training1962 M.B.,Ch.B University of Baghdad, Baghdad, Iraq1965-1967 Resident in Medicine Republican Teaching Hospital, Baghdad, Iraq1967-1968 Fellow in Medicine Baltimore City Hospital, Baltimore, MD1968-1969 Resident in Medicine Baltimore City Hospital, Baltimore, MD1969-1970 Fellow in Medicine Johns Hopkins Hospital, Baltimore, MD1970-1971 Fellow in Medicine Massachusetts General Hospital, Baltimore, MDHonors and Awards2005 Stevens Triennial Prize. Columbia University College of P & S.2005 Fellow,American Academy of Arts & Sciences2006 Distinguished Achievement Award University of Iowa, Dept of Medicine2007 Homer W. Smith Award; American Society of Nephrology2008 Ewig Clinical Scholar Award Columbia University, Dept of Medicine2009 The Harvey Lecture;The Harvey Society2010 Princess Liliane of Belgium Award Princess Liliane Foundation2010 Robert W Berliner Award. American Physiological Society, Renal Excellence in Renal Physiology SectionCommittees and Society Memberships1972 American Society of Nephrology (Chairman Committee, Program of Annual Meeting year 2001)1972 International Society of Nephrology1972 American Federation for Clinical Research1974 Society of General Physiologists1975 American Physiological Society1975 Central Society for Clinical Research1977 Salt and Water Club (Secretary 1982?1985)1978 American Society for Clinical Investigation1980-85 NIH Physiology Study Section1984 American Society of Cell Biology1986 Association of American Physicians1989 Fellow, American Association for the Advancement of Science1991-95 Research Committee, American Heart Association/NYC Chapter1991 Interurban Clinical Club1992-‘97. Scientific Advisory Board on Intramural Research, NIDDKD1994 Practitioners Society of New YorkSpecial InterestsEpithelial Cell biologyIon channelsDevelopment of the KidneySelected Publications:1. Oliver JA, Barasch J, Yang J, Herzlinger D, Al-Awqati Q. (2002 ) Metanephric mesenchyme contains embryonic renal stem cells. Am J Physiol Renal Physiol 283(4):F799-809 2. Al-Awqati Q. (2003) Terminal differentiation of intercalated cells: the role of hensin. Annu Rev Physiol :567-83 3. Al-Awqati Q, Oliver JA. (2002) Stem cells in the kidney. Kidney Int 61(2):387-95 4. Schwartz GJ, Tsuruoka S, Vijayakumar S, Petrovic S, Mian A, Al-Awqati Q. (2002) Acid incubation reverses the polarity of intercalated cell transporters, an effect mediated by hensin. J Clin Invest 109(1):89-99 5. Hikita C, Vijayakumar S, Takito J, Erdjument-Bromage H, Tempst P, Al-Awqati Q. (2000) Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3. J Cell Biol 151(6):1235-46 6. Al-Awqati Q. (1999) One hundred years of membrane permeability: does Overton still rule? Nat Cell Biol 1(8):E201-2الدكتور كمال حسين صالح الحسينياستشاري تجميلdrkhsh2001@ymail.com | |
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